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Percocet is a prescription opioid painkiller that is used to treat moderate to severe pain. It is a combination of oxycodone and acetaminophen. Oxycodone is an opioid that works by binding to opioid receptors in the brain and spinal cord. This binding blocks pain signals from being sent to the brain. Acetaminophen is a non-opioid pain reliever that works by inhibiting the production of prostaglandins, which are chemicals that cause pain and inflammation

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