https://campaigns.vibha.org/campaigns/modafinil%2025
In 2026, modafinil remains the quintessential wakefulness-promoting agent (eugeroic), distinguished by its ability to foster a state of natural alertness without the intense physiological strain of traditional stimulants. Unlike amphetamines that broadly trigger the "fight or flight" response, modafinil acts with surgical precision on the brain's sleep-wake centers, primarily by increasing dopamine levels and stimulating the orexin and histamine pathways in the hypothalamus. This selective mechanism helps individuals with narcolepsy, obstructive sleep apnea, and shift work disorder maintain cognitive performance and vigilance throughout the day. While it is celebrated for its lower poten