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Methadone is a synthetic opioid medication primarily used for the management of opioid dependence and chronic pain. It operates as a long-acting agonist of the mu-opioid receptor, which means it binds to the same receptors in the brain as other opioids, such as morphine or heroin. First developed in the 1930s, methadone has gained prominence in the treatment of opioid addiction, helping individuals taper off more potent narcotics and manage withdrawal symptoms during the recovery process. As an integral component of medication-assisted treatment (MAT), methadone plays a critical role in addressing opioid use disorder (OUD) while minimizing the risks associated with illicit drug use.
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