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In addition to its pain-relieving properties, tramadol also affects certain neurotransmitters in the brain, such as serotonin and norepinephrine. This dual mechanism of action sets tramadol apart from other opioids and may provide additional benefits for certain types of pain.

It is important to note that tramadol carries a risk of dependence and abuse, similar to other opioids. Therefore, it should only be used under the supervision of a healthcare professional and in accordance with the prescribed dosage and duration of treatment. Misuse or taking higher doses than prescribed can lead to serious side effects, including respiratory depression, sedation, and even overdose.