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Synthetic opioids like tramadol are a class of medication that helps lessen extremely painful situations. By obstructing the nerves' ability to transmit pain signals from the brain to the body, tramadol decreases feelings of pain by acting directly on opioid receptors in the central nervous system. Short-term use of this medication may result in side effects; in this case, you should see a doctor. Long-term use of this medication may also cause side effects.