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Oxycodone vs Codeine: Which Opioid Offers Stronger Pain-Relief Benefits?


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Oxycodone and codeine are both prescription opioids used to manage pain, but they differ significantly in strength and effectiveness. Oxycodone is a more potent opioid, often prescribed for moderate to severe pain, such as post-surgical pain or cancer-related discomfort. It works by binding strongly to opioid receptors in the brain and spinal cord, providing significant relief. In contrast, codeine is a weaker opioid, typically used for mild to moderate pain and sometimes in combination with acetaminophen or other non-opioid pain relievers.

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