CAR T-cell therapy has revolutionized cancer treatment, particularly for blood cancers. However, several limitations still hinder its broader application and effectiveness.
Treatment Accessibility
Limited Availability: CAR T-cell therapy is only available in select specialized hospitals, often in major cities or academic centers. Its accessibility is restricted, especially in rural or underdeveloped regions, limiting the number of patients who can benefit from it.
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Side Effects and Safety
Cytokine Release Syndrome (CRS): One of the most severe side effects of CAR T-cell therapy is CRS, which can cause fever, low blood pressure, and organ damage.
Limitations of CAR T-Cell Therapy in Cancer Treatment in Croatia
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