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Chimeric Antigen Receptor T-cell (CAR T-cell) therapy represents one of the truly breakthrough therapeutic approaches to blood cancers, including leukemia and lymphoma. This novel immunotherapy manipulates a patient's T cells to engender far greater cancer-cell targeting ability. With the dramatic thrust provided by increasing experience with CAR T-cell therapy, how patients are treated for their hematologic malignancies is truly being transformed while providing patients with treatment options that are otherwise not possible with cancer in these malignancies.
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